In this study we generate an integral model to remove Cu (II) in waters using the spherical agglomeration technique, determining a wide interval of metal concentrations in the water models.

A modification in the hydrophobization step of this technique is suggested by substituting high-cost industrial tensoactive agents with high sodium content, for biosurfactants enriched with saponines and free of sodium.

Extracts are generated, with a wide dosification spectrum involving lechuguilla (Agave lechuguilla Torr.) pulp as biosurfactant, which constitutes subproduct waste from several agroindustries in Mexico.

An experimental design is developed as well as a statistical analysis for the Cu(II) removal method in wate, which demonstrate the efficiency of the use of lechuguilla extracts as biosurfactant with this technique.

The design of this method considers the optimal stoichiometric relations for all the removal stages, reaching residual concentrations of Cu(II), sodium and calcium that widely satisfy the current legislation in water quality..